Endocrine Abstracts

Introduction: Hypercalcaemia accounts for 0.6% of all acute medical admissions1, with primary hyperparathyroidism and malignancy-associated hypercalcaemia contributing to 90% of these cases.Case Presentation: A 67-year-old female was initially seen in neurology clinic with a 3-year history of subtle word-finding difficulties, episodic confusion, and balance problems. On further probing, she reported constipation, polyuria and polydipsia, but h...

Background: Bariatric surgery significantly aids weight loss, improves glycaemic control and/or induces remission in Type 2 Diabetes patients. However, the impact of bariatric surgery in Type 1 diabetes (T1D) patients is less well-understood. With an increasing prevalence of obesity within the T1D population, it is important to identify whether bariatric surgery improves glycaemic control and prevents future complications.Aim: To evaluate the effect on B...

Background: Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycaemic state (HHS) are common diabetic emergencies. However, the associated morbidity and mortality remains substantial. Non-specialist trainee healthcare professionals (HCPs) are usually the first point of contact in managing these patients in the acute medical setting. It is therefore essential that these trainees are confident in the management of these emergencies. Aims: Our aim was to ...

Introduction: PTEN Hamartoma Tumor Syndrome (PHTS)is a rare genetic spectrum of disorders characterised by multiple hamartomas and increased risk of cancers including thyroid cancer. People with PHTS have an increased lifetime risk of differentiated thyroid carcinoma (DTC), estimated to be about 35% compared to the general population risk of below 1% (1). Case Presentation: We report a 38-year-old male who presented with a Goitre found on routine examina...

Introduction: Pseudohypoparathyroidism (PHP) is a rare cause of hypocalcaemia due to parathyroid hormone (PTH) resistance in the proximal renal tubules. In contrast to PHP type 1A, PHP type 1B is characterised by the absence of the characteristic skeletal abnormalities and is transmitted in an autosomal dominant manner, but in the maternal line. Patients may have resistance to the action of other G-protein signaling hormones, like thyroid stimulating hormone (TSH).<p class...